Correlations of cardiovascular classical risk factors in patients with STEMI and the No-Reflow phenomenon after primary PCI

Introduction: Following an acute myocardial infarcti-on, it is essential to perform primary PCI urgently to reperfusion the coronary artery involved, restoring optimal flow to this level. However, the post stent implan-tation of a TIMI 0-1 flux and the presence of a MGB 0-1 translates the coronary no-reflow phenomenon with a negative prognosis.

Methods: A study was conducted on 656 patients ad-mitted to the County Emergency Clinical Hospital of Oradea between 01.01.2016 and 31.03.2018 who pre-sented STEMI, and following primary PCI, 96 deve-loped coronary no-reflow phenomenon. The patients were clinically and paraclinically assessed: ECG and pre-post-PCI echocardiography, TIMI and MGB flow assessment, and the epicardial coronary arteries invol-ved.

Results: In both groups the male sex prevailed 65.71% in the Normal flow group and 66.67% in the No reflow group), the male sex is not a risk factor for the pheno-menon noreflow. Age over 50 increases the risk of no-reflow phenomenon (OR=1.887, p=0.010). The higher the age, the greater the risk. Thus, in patients aged less than 50 years, in patients aged 51-70 years, the risk is 1.7 times higher and in patients over 70 years the risk is 2.2 higher High blood pressure, irrespective of its degree, is not a risk factor for the occurrence of no-reflow phenomenon (OR=1.250, p=0.297). Regardless of the type of diabetes (insulin-dependent or non-in-sulin-dependent), diabetic patients have a risk of no-reflux occurring almost twice as high as non-diabetic (OR=1.951, p<0.001). Dyslipidemia, smoking and ge-netic factor are potent risk factors for noreflow phe-nomenon (OR=3.335, p<0.001, OR=1.778, p=0.003, OR=1.854, p=0.004). Existence of renal disease is also a strong risk factor for the occurrence of norelow pheno-menon (OR=3.140, p<0.001).

Conclusions: The knowledge and the establishment of the complete profile of cardiovascular risk factors ren-defines their impact on the population through the de-termined fatal cardiovascular events and the ischemic cardiovascular disease by increasing the incidence of acute myocardial infarction is evaluated as the main ca-use of morbidity and mortality among the population.

ISSN – online: 2734 – 6382
ISSN-L 1220-658X
ISSN – print: 1220-658X
The Romanian Journal of Cardiology is indexed by:
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CODE: 379
CME Credits: 10 (Romanian College of Physicians)
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